A na-enyocha acid Organic na akwụkwọ, mgbọrọgwụ na karịsịa mkpụrụ osisi nke ọgwụ ahịhịa ndị China.Acids ndị a na-ahụkarị bụ carboxylic acid, acidity nke sitere na otu carboxyl (-COOH).Ọtụtụ acid organic bụ ihe dị mkpa akụrụngwa akụrụngwa, dị ka citric acid, dibasic acid, lactic acid, itaconic acid na ndị ọzọ.Site n'ịbawanye ụba nke acid organic, otu esi ebelata ọnụ ahịa mmepụta, melite ogo ngwaahịa, na ịchekwa ike na ibelata ikuku abụrụla ihe ụlọ ọrụ na-elekwasị anya.Ya mere, ịkwalite usoro mmịpụta nke organic acid aghọwo otu n'ime ụzọ asọmpi maka ndị na-emepụta acid organic.Taa, onye nchịkọta akụkọ nke Shandong Bona Group ga-ewebata ngwa nke teknụzụ nkewa akpụkpọ ahụ na mmepụta nke acid organic.
Dị ka otu n'ime teknụzụ pretreatment maka nkewa na mmịpụta nke citric acid, teknụzụ ultrafiltration bụ usoro ọhụrụ nke pụtara naanị n'afọ ndị na-adịbeghị anya.Ọ bụ usoro nyocha anụ ahụ dị mfe.Enwere ike iji ya wepụ na ikewapụ adịghị ọcha dị ka protein, sugars, na pigments na nzacha.Isi ihe na usoro a bụ ịhọrọ membranes ultrafiltration nwere nguzogide oxidation ka mma yana nguzogide acid.Membrane nkewa na filtration nke organic acid gbaa ụka efere kpamkpam wepụ macromolecular proteins, colloid, bacteria, polysaccharides na ndị ọzọ adịghị ọcha na gbaa ụka efere na molekụla larịị.Ihe nzacha ahụ nwere nghọta dị elu na ịdị ọcha nke acid organic.Ọ na-enyere aka ịchịkwa nsị mmiri na-esote ma melite ogo ngwaahịa na mkpụrụ.
Usoro nke iwepụta organic acid site na usoro ultrafiltration:
Organic acid gbaa ụka broth pretreatment → ultrafiltration → crystallization → centrifuged nne mmanya → ihicha → ngwaahịa emechara
Uru nke teknụzụ nkewa nke akpụkpọ ahụ acid organic:
1. Teknụzụ nkewa nke membrane na-edochi usoro nzacha nke efere ọdịnala na nke etiti, na-akọwapụta broth ịgba ụka, na-eme ka mma nke filtrate dịkwuo mma, ma na-ebelata mmetọ resin na usoro na-esote;
2. Ngwá ọrụ akpụkpọ ahụ na-arụ ọrụ na okpomọkụ nke ụlọ, na-azọpụta ike na-enweghị ibibi ihe ndị na-arụ ọrụ na ngwaahịa ahụ;
3. Ọ dịghị mkpa ịgbakwunye kemịkalụ, ihe mgbaze, na mmetọ nke abụọ na usoro nzacha;
4. Membrane usoro ihe niile na-mere nri ịdị ọcha ọkwa igwe anaghị agba nchara, n'ụzọ zuru ezu mechie pipeline ọrụ, na izute chọrọ nke GMP mmepụta nkọwa.Usoro ahụ na-akwado nhazi usoro nhazi, nke na-etinye obere oghere n'ala ma nwee nhazi ezi uche;
5. Ihe membrane na ihe inyeaka na-enye aka bụ ihe na-adịghị emetọ ihe, kwekọrọ na QS na GMP chọrọ.
Bona Bio bụ onye nrụpụta ọkachamara na-emepụta akụrụngwa nkewa akpụkpọ ahụ.Ọ nwere ọtụtụ afọ nke mmepụta na teknuzu ahụmahụ, na-elekwasị anya na-edozi nsogbu nke filtration na itinye uche na mmepụta usoro nke ndu gbaa ụka / ihe ọṅụṅụ / omenala Chinese ọgwụ / anụmanụ na osisi mmịpụta.Usoro mmepụta okirikiri nwere ike inyere ndị ahịa aka imeziwanye mmepụta mmepụta ma nweta mmepụta dị ọcha.Ọ bụrụ na ị chere nsogbu ọ bụla ihu na nzacha akpụkpọ ahụ, biko nweere onwe gị ịkpọtụrụ anyị, anyị ga-enwe ndị ọkachamara ọkachamara ka ha zaa gị.
Oge nzipu: Eprel-20-2022